Biology and Bioengineering
ZHOU Yongjin
Title: Professor
Subject: Biotechnology
Phone:
Email: zhouyongjin@dicp.ac.cn
Website:
Research Interests

Synthetic biology, metabolic engineering, C1 biotechnology.

 

Engineering microbial (yeast) cell factories for production of chemicals, biofuels and bioactive molecules by developing synthetic biology tools and metabolic engineering principles

Biography
Professor, Dalian Institute of Chemical Physics, CAS, 2018/02 - present 
Associate Professor, Dalian Institute of Chemical Physics, CAS, 2017/01 - 2018/02 
Postdoc, Chalmers University of Technology, Sweden, 2012/06 - 2016/12 
Ph.D. in Biochemical Engineering, Dalian Institute of Chemical Physics, CAS, 2008/09 - 2012/06 
M.S. in Biochemical Engineering, Tianjin University, 2006/09 - 2008/07 
B.S. in Food Science and Technology, Jiangnan University, 2002/09 - 2006/07
Honors and Awards
Zhang Dayu Chair professor, 2021 
The Best Potential Youth Scholar, 2019 
Excellent Young Scholars from NSFC, 2019 
"Lun Shiyi" Distinguished Young Scientists, 2018 
National Talent Program for Young Scientists, 2018 
Young Scholar Award in the Chemical Engineering from NSFC, 2017 
Young Scholar Award of International Metabolic Science Conference, 2016 
The first prize of Chinese Pharmaceutical Association, 2015
Publications

1. Jiaoqi Gao, Yunxia Li, Wei Yu, Yongjin Zhou*, Rescuing yeast from cell death enables overproduction of fatty acids from sole methanol, Nature Metabolism, 2022, 4, 932-943.

2. Peng Cai, Xiaoyan Wu, Jun Deng, Yongjin Zhou*, Methanol biotransformation toward high-level production of fatty acid derivatives by engineering the industrial yeast Pichia pastoris, Proceedings of the National Academy of Sciences of the United States of America, 2022, 119(29), e2201711119.

3. Ruibing Chen, Jiaoqi Gao, Wei Yu, Xianghui Chen, Xiaoxin Zhai, Yu Chen, Lei Zhang*, Yongjin Zhou*, Engineering cofactor supply and recycling to drive phenolic acid biosynthesis in yeast. Nature Chemical Biology, 2022, 18(5), 520-529.

4. Peng Cai#, Xingpeng Duan#, Xiaoyan Wu, Linhui Gao, Min Ye, Yongjin Zhou*, Recombination machinery engineering facilitates metabolic engineering of the industrial yeast Pichia pastoris. Nucleic Acids Research, 2021, 49(13), 7791–7805

5. Jiaoqi Gao, Ning Gao, Xiaoxin Zhai, Yongjin Zhou*, Recombination machinery engineering for precise genome editing in methylotrophic yeast Ogataea polymorpha, iScience, 2021, 24(3), 102168

6. Ruibing Chen, Shan Yang, Lei Zhang, Yongjin Zhou*, Advanced strategies for production of natural products in yeast. iScience, 2020, 23, 100879.

7. Tao Yu#, Yongjin Zhou#, Mingtao Huang, Quanli Liu, Rui Pereira, Florian David, Jens Nielsen*, Reprogramming yeast metabolism from alcoholic fermentation to lipogenesis. Cell. 2018, 174(6), 1549-1558.

8. Yongjin Zhou, Eduard Kerkhoven, Jens Nielsen*, Barriers and opportunities in bio-based production of hydrocarbons. Nature Energy, 2018, 3, 925-935.

9. Yongjin Zhou*, Yating Hu, Zhiwei Zhu, Verena Siewers, Jens Nielsen*, Engineering 1-alkene biosynthesis and secretion by dynamic regulation in yeast. ACS Synthetic Biology, 2018, 7(2), 584-590.

10. Zhiwei Gong, Jens Nielsen*, Yongjin Zhou*, Engineering robustness of microbial cell factories. Biotechnology Journal, 2017, 12(10), 1700014.