Chemistry and Chemical Engineering
LU Xin
Title: Professor
Subject: Applied Chemistry
Phone: 0411-84379532
Email: luxin001@dicp.ac.cn
Website:
Research Interests

Research Interests

1. High resolution and sensitivity analytical methods

2. Novelanalytical method and techniquesfor metabolomics/metabonomics

3. Plant metabolomics

Main research funds 

1. Natural Science Foundation of China, Project number21375127, “Development of a novel 'pseudo' targeted LC-MS metabolic profilingmethod and its application in prostatic cancer”2014/01-2017/12 

2. Ministry of Science and Technology of China, Project number 2012CB518303,“Omics features and the key targets in Chinese human prostate cancer”, 2012/01-2016/08

Biography
Professor Xin Lureceived Bachelor degree (in 1989) and Master degree (in 1993) in fine chemical from Dalian University of Technology. She obtained her Ph.D. from Dalian Institute of Chemical physics (DICP), Chinese Academy of Sciences (CAS) in 2004.She was promoted to associate Professor in 2001 and Professor in 2009.She haspublished more than 100 peer-reviewedpapers, and applied more than 30 patents.She participated in many projects from NSFC, State Key Fundamental Research “863”, ”973” and Knowledge Innovation Program of CAS.Her main research interest is the characterization and separation of complex mixtures using chromatography in combination with mass spectrometry.
Honors and Awards
Time Honors and Awards 
2011 "Chromatography-mass spectrometry based metabonomics analytical platform and it’s applications", Liaoning Province Second Prize for Technical Innovation (Rank 3)  
Publications

1. "Pseudotargeted Metabolomics Method and Its Application in Serum Biomarker Discovery for Hepatocellular Carcinoma Based on Ultra High-Performance Liquid Chromatography/Triple Quadrupole Mass Spectrometry", Chen, S.; H. Kong; X. Lu; Y. Li; P. Yin; Z. Zeng; G. Xu, Anal. Chem. 85 (17), 8326-8333(2013)

2. "Investigation of the Relationship between the Metabolic Profile of Tobacco Leaves in Different Planting Regions and Climate Factors Using a Pseudotargeted Method Based on Gas Chromatography/Mass Spectrometry", Zhao, Y.; C. Zhao; X. Lu; H. Zhou; Y. Li; J. Zhou; Y. Chang; J. Zhang; L. Jin; F. Lin; G. Xu, J. Proteome Res. 12 (11), 5072-5083(2013)

3. "Analysis of free amino acids in flue-cured tobacco leaves using ultra-high performance liquid chromatography with single quadrupole mass spectrometry", Zhang, J.; C. Zhao; Y. Chang; Y. Zhao; Q. Li; X. Lu; G. Xu, J. Sep. Sci. 36 (17), 2868-2877(2013)

4. "Alteration of Leaf Metabolism in Bt-Transgenic Rice (Oryza sativa L.) and Its Wild Type under Insecticide Stress", Zhou, J.; L. Zhang; Y. Chang; X. Lu; Z. Zhu; G. Xu, J. Proteome Res. 11 (8), 4351-4360(2012)

5. "Analysis of Urinary Metabolic Signatures of Early Hepatocellular Carcinoma Recurrence after Surgical Removal Using Gas Chromatography-Mass Spectrometry", Ye, G.; B. Zhu; Z. Yao; P. Yin; X. Lu; H. Kong; F. Fan; B. Jiao; G. Xu, J. Proteome Res. 11 (8), 4361-4372(2012)

6. "A novel approach to transforming a non-targeted metabolic profiling method to a pseudo-targeted method using the retention time locking gas chromatography/mass spectrometry-selected ions monitoring", Li, Y.; Q. Ruan; Y. Li; G. Ye; X. Lu; X. Lin; G. Xu, J. Chromatogr. A 1255, 228-236(2012)

7. "Serum 27-nor-5 beta-Cholestane-3,7,12,24,25 PentolGlucuronide Discovered by Metabolomics as Potential Diagnostic Biomarker for Epithelium Ovarian Cancer", Chen, J.; X. Zhang; R. Cao; X. Lu; S. Zhao; A. Fekete; Q. Huang; P. Schmitt-Kopplin; Y. Wang; Z. Xu; X. Wan; X. Wu; N. Zhao; C. Xu; G. Xu, J. Proteome Res. 10 (5), 2625-2632(2011)

8. "Accelerated solvent extraction for GC-based tobacco fingerprinting and its comparison with simultaneous distillation and extraction", Li, Y.; T. Pang; Z. Guo; Y. Li; X. Wang; J. Deng; K. Zhong; X. Lu; G. Xu, Talanta 81 (1-2), 650-656(2010)

9. "Application of Fuzzy c-Means Clustering in Data Analysis of Metabolomics", Li, X.; X. Lu; J. Tian; P. Gao; H. W. Kong; G. W. Xu, Anal. Chem. 81 (11), 4468-4475(2009)