Chemistry and Chemical Engineering
SUI Zhigang
Title: Associate Professor
Subject: Analytical Chemistry,Biotechnology
Phone:
Email: zhigangsui@dicp.ac.cn
Website:
Research Interests
Proteomics, extracellualr vesicles, velvet antler, tissue engineering
1. Study on bioactive protein fractions extracted from velvet antler, and the critical regulatory factor by using proteomics strategy. 
2. Investigation on the isolation, purification and proteomics analysis of exosomes from conditioned media, urine and blood. 
3. Exploration on the mechanisms of some regeneration models (such as Velvet Antler stem cell) by characterizing the secretome profiling.
Biography
1. Associate Professor, Dalian Institute of Chemical Physics, Chinese Academy of Sciences (CAS), 2019/06 - present 
2. Visiting Scholar, Ben May Department of Cancer Research, The University of Chicago, USA, 2018/12 - 2019/12 
3. Associate Professor, Dalian Institute of Chemical Physics, CAS, 2013/07 - 2018/12 
4. Lecturer of pathogen biology, Faculty of Norman Bethune College of Medicine, Jilin University, 2009/07 - 2011/02 
5. Ph.D. in biochemistry and molecular biology, Jilin University, 2006/09 - 2009/07 
6. M.S. in Pharmaceutical Analysis, Jilin University, 2003/09 - 2006/07 
7. B.S. in Pharmacy, Jilin University, 1998/09 - 2002/06
Honors and Awards
 
Publications
1. Di Chen, Xinjie Zhao, Zhigang Sui, Huan Niu, Luonan Chen, Cheng Hu, Qiuhui Xuan, Xuhong Hou, Rong Zhang, Lina Zhou, Yanli Li, Huiming Yuan, Yukui Zhang, Jiarui Wu, Lihua Zhang*, Ren'an Wu*, Hai-Long Piao*, Guowang Xu* and Weiping Jia*. A Multi-Omics Investigation of the Molecular Characteristics and Classification of Six Metabolic Syndrome Relevant Diseases. Theranostics, 2020, 5, 2029-2046. 
2. Lingfan Chen, Yichu Shan, Chao Yang, Zhigang Sui, Xiaodan Zhang, Lihua Zhang* and Yukui Zhang. Carboxypeptidase B-Assisted Charge-Based Fractional Diagonal Chromatography for Deep Screening of C-Terminome. Analytical Chemistry, 2020, 12, 8005-8009. 
3. Yechen Hu, Bo Jiang, Yejing Weng, Zhigang Sui, Baofeng Zhao, Yuanbo Chen, Lukuan Liu, Qiong Wu, Zhen Liang, Lihua Zhang* and Yukui Zhang. Bis(Zinc(Ii)-Dipicolylamine)-Functionalized Sub-2 Mu M Core-Shell Microspheres for the Analysis of N-Phosphoproteome. Nature Communications, 2020, 11, 6226. 
4. Ting Li, Zhigang Sui, Akira. Matsuno, Hirotomo. Ten, Kenichi. Oyama, Akihiro. Ito, Hong. Jiang, Xiaomin Ren, Rabia. Javed, Lihua Zhang* and Qiang Ao*. Fabrication and Evaluation of a Xenogeneic Decellularized Nerve-Derived Material: Preclinical Studies of a New Strategy for Nerve Repair. Neurotherapeutics, 2020, 1, 356-370. 
5. Hongmei Sun, Zhigang Sui, Datao Wang, Hengxing Ba, Haiping Zhao, Llihua Zhang* and Chunyi Li*. Identification of Interactive Molecules between Antler Stem Cells and Dermal Papilla Cells Using an in Vitro Co-Culture System. Journal of Molecular Histology, 2020, 1, 15-31. 
6. Zhigang Sui, Hongmei Sun, Yejing Weng, Xiaodan Zhang, Mingwei Sun, Rui Sun, Baofeng Zhao, Zhen Liang, Yukui Zhang, Chunyi Li* and Lihua Zhang*. Quantitative proteomics analysis of deer antlerogenic periosteal cells reveals potential bioactive factors in velvet antlers. Journal of chromatography A, 2020，1609, 460496. 
7. Rui Huo, Yilan Li, Zhigang Sui, Huiming Yuan, Kaiguang Yang, Zhen Liang, Yukui Zhang and Lihua Zhang*. Advances in exosome isolation methods and their applications in proteomic analysis of biological samples. Analytical and Bioanalytical Chemistry, 2019, 411, 5351-3361. 
8. Xinlu Liu, Yejing Weng, Peng Liu, Zhigang Sui, Lei Zhou, Yingpeng Huang, Lihua Zhang*, Yukui Zhang and Xiaodong Tan*. Identification of PGAM1 as a putative therapeutic target for pancreatic ductal adenocarcinoma metastasis using quantitative proteomics. Onco Target and Therapy, 2018, 11, 3345-3357. 
9. Na Li, Zhigang Sui (co-first author), Yong Liu, Dandan Wang, Guangbo Ge and Ling Yang*. A fast screening model for drug permeability assessment based on native small intestinal extracellular matrix. RSC Advances, 2018, 8, 34514-34524.