1. Development of enrichment materials and methods for analysis of protein post-translational modification.
2. Finding drug targets of the bioactive compounds from traditional Chinese medicine.
3. Decoding the signaling pathways of drugs.
1. 2020/09-present: Dalian Institute of Chemical Physics, CAS, Group leader
2. 2017/07-present: Dalian Institute of Chemical Physics, CAS, Professor
3. 2009/10-2017/06: Dalian Institute of Chemical Physics, CAS, Associate Professor
4. 2006/10-2009/09: Dalian Institute of Chemical Physics, CAS, Assistant Professor
5. 2004/03-2006/02 Max-Planck Institute of Biochemistry, Germany, Post-doc
6. 2000/09-2004/02: Dalian Institute of Chemical Physics, CAS, Ph.D, Analytical Chemistry
7. 1993/09-2000/07: Northeast Normal University, B.S. and M.S., Chemistry
1. Xiong YT#, Li XL#, Li MM, Qin HJ, Chen C, Wang DD, Wang X, Zheng XT, Liu YH, Liang XM*, Qing GY*. What is hidden behind Schiff base hydrolysis? Dynamic covalent chemistry for precise capture of sialylated glycans, J. Am. Chem. Soc. 2020, 142, 7627
2. Lu Q, Chen C, Xiong YT, Li GD, Zhang XF, Zhang YH, Wang DD, Li XL*, Qing GY*, Sun TL, Liang XM. High-efficiency phosphopeptide and glycopeptide simultaneous enrichment by hydrogen bond–based bi-functional smart polymer, Anal. Chem. 2020, 92, 9, 6269
3. Song YY#, Li XL#, Fan JB#, Kang HJ, Zhang XF, Liang XM* and Wang ST*. Interfacially polymerized particles with heterostructured nanopores for glycopeptide separation, Adv. Mater., 2018, 30, 1803299
4. Qing GY, Lu Q, Li XL*, Liu J, Ye ML, Liang XM*, Sun TL*. Hydrogen bond-based smart polymer for highly selective and tunable capture of multiply phosphorylated peptides, Nat. Commun., 2017, 8, 461
5. Li XL#, Xiong YT#, Qing GY, Jiang G, Li XQ, Sun TL*, Liang XM*. Bioinspired saccharide-saccharide interaction and smart polymer for specific enrichment of sialylated glycopeptides, ACS Appl. Mater. Interfaces, 2016, 8, 13294