Chemistry and Chemical Engineering
QIN Hongqiang
Title: Professor
Subject: Analytical Chemistry
Phone: 0411-84379620
Email: qinhq@dicp.ac.cn
Website:
Research Interests
His research interest is focused on the new techniques for glycoproteomics sample pretreatment, including functional material for the enrichment of glycoproteins/ peptides, and the characterization the micro-heterogeneity of glycosylation on the levels of glycan structures, glycosites and site-specific glycoforms. As the principal investor, he is responsible for the foundations from the National Natural Science Foundation of China and Chinese Academy of Sciences. More than 60 SCI papers have been published, with more than 1200 citation (H-index: 24).
Biography
Hongqiang Qin, Professor of Analytical Chemistry, born in Shandong Province in 1984, works in CAS Key Laboratory of Separation Sciences for Analytical Chemistry, Dalian Institute of Chemical Physics (DICP), Chinese Academy of Sciences (CAS). He obtained his B.S. Medicine from Tianjin University in 2007, Ph.D. Analytical Chemistry from Dalian Institute of Chemical Physics (DICP) 2013 (Supervisor: Prof. Hanfa Zou and Prof. Ren’an Wu). He started his career at DICP, July, 2013, and was elected ‘Excellent Young Scholars of DICP’ as the Associate Professor. He was promoted as the Professor, July, 2018.
Honors and Awards
He is also the Member of Youth Innovation Promotion Association, CAS (2018-2021);
Publications
1. Hongqiang Qin#, Kai Cheng#, Jun Zhu#, Jiawei Mao, Fangjun Wang, Mingming Dong, Rui Chen, Zhimou Guo, Xinmiao Liang, Mingliang Ye, Hanfa Zou, Proteomics Analysis of O-GalNAc Glycosylation in Human Serum by an Integrated Strategy, Anal. Chem., 2017, 89, 1469-1476. (Co-first author).
2. Xuefang Dong#, Hongqiang Qin#, Jiawei Mao, Dongping Yu, Xiuling Li, Aijin Shen, Jingyu Yan, Long Yu, Zhimou Guo, Mingliang Ye, Fanfa Zou, Xinmiao Liang, In-depth Analysis of Glycoprotein Sialylation in Serum Using a Dual-Functional Material with Superior Hydrophilicity and Switchable Surface Charge, Anal. Chem., 2017, 89, 3966-3972. (Co-first author).
3. Jian Wu#, Hongqiang Qin#, et al. Characterization of site-specific glycosylation of secreted proteins associated with multi-drug resistance of gastric cancer, Oncotarget, 2016, 7, 18, 25315-25327. (Co-first author).
4. Junfeng Huang, Hongqiang Qin, et al. A peptide N-terminal protection strategy for comprehensive glycoproteome analysis using hydrazide chemistry based method. Sci. Report, 2015, 5, 10164, 1-15.
5. Junfeng Huang, Hongqiang Qin, et al. In Situ Sample Processing Approach (iSPA) for Comprehensive Quantitative Phosphoproteome Analysis, J. Proteome Res., 2014, 13, 3896-3904.
6. Ruibin Li, Zhaoxia Ji, Hongqiang Qin,  et al. Interference in Autophagosome Fusion by Rare Earth Nanoparticles Disrupts Autophagic Flux and Regulation of an Interleukin-1β Producing Inflammasome, ACS Nano, 2014, 8, 10280-10292.
7. Hongqiang Qin, Zhengyan Hu, et al. Facile preparation of ordered mesoporous silica–carbon composite nanoparticles for glycan enrichment Chem. Commun., 2013, 49, 5162-5165.
8. Zhichao Xiong, Hongqiang Qin, et al. Layer-by-layer assembly of multilayer polysaccharide coated magnetic nanoparticles for the selective enrichment of glycopeptides Chem. Commun., 2013, 49, 9284-9286.
9. Hao Wan, Hongqiang Qin, et al. Facile synthesis of yolk- shell magnetic mesoporous carbon microspheres for efficient enrichment of low abundance peptides, Nanoscale, 2013, 5, 10936–10944.
10. Hongqiang Qin, Fangjun Wang, et al. Phosphoric acid functionalized mesoporous organo-silica (EPO) as the adsorbent for in situ enrichment and isotope labeling of endogenous phosphopeptides, Chem. Commun., 2012, 48, 961–963.
11. Hongqiang Qin, Fangjun Wang, et al. Isobaric cross- sequence labeling of peptides by using site-selective N-terminus dimethylation. Chem. Commun., 2012, 48, 6265-6267.
12. Hongqiang Qin, Peng Gao, et al. Highly Efficient Extraction of Serum Peptides by Ordered Mesoporous Carbon, Angew. Chem. Inter. Edit., 2011, 50, 12218 –12221.
13. Hongqiang Qin, Liang Zhao,   Size-Selective Enrichment of N-Linked Glycans Using Highly Ordered Mesoporous Carbon Material and Detection by MALDI-TOF MS, Anal. Chem, 2011, 83, 7721–7728.