(1) High Efficient Ambient Ionization Technology and Mechanism: focus at the generally used ionization sources in IMS and MS such as photoionization, electric spray, chemical ionization, and etc., explore their mechanism of ion-molecular reactions and the related influencing factors, build up theoretical foundations for the design of advanced ionization sources;

(2) Ultra High Resolution Ion Mobility Spectrometry: study the ion motion behaviors under the coupling of multiple physical fields such as temperature, airflow, and electric field from bar to mbar pressures, explore the key factors affecting ion high fidelity transmission and efficient separation, and provide theoretical guidance for the design of miniaturized ion mobility spectra, ultra-high resolution TIMS, and TIMS;

(3) Multidimensional Spectrometry Technology: solve the key technical problems such as efficient sample utilization, ion non-destructive transmission, and time-domain matching in interfacing IMS with GC, MS, and etc., to support the development of rapid detection technology and instruments of multidimensional spectrometry.

(1) Youth Excellence Award, Dalian Institute of Chemical Physics, 2019

(2) Second prize of provincial technological invention, Liaoning Province, 2017

(3) First prize of municipal technological invention, Dalian, 2016

[1]  Shiwen Cheng, Qiang Han, Yumei Qin, Li Chen, Yuezhong Mao, Jianmei Yang, Ruihang Zheng, Jianzhong Han, Zihan Qin*, Chuang Chen*, Shiyi Tian*, Thermal desorption-photoionization ion mobility-electronic nose (TD-PIM-Nose) with distance-probability joint decision SVM algorithm: A novel system for Daqu Grade identification, Food Chemistry, 2025, 463(3):141360

[2]  Yiqian Xu, Qimu Yang, Manman Pan, Dandan Jiang, Yi Yu, Chuang Chen*, Haiyang Li*, Improving the Sensitivity and Linear Range of Photoionization Ion Mobility Spectrometry via Confining the Ion Recombination and Space Charge Effects Assisted by Theoretical Modeling, Analytical Chemistry, 2024, 96:3979-3987

[3]  Qimu Yang, Yiqian Xu, Manman Pan, Dandan Jiang, Zhenxin Wang, Weiguo Wang, Xianzhe Shi, Chuang Chen*, Haiyang Li*, Enhancing the Performance of Tyndall–Powell Gate Ion Mobility Spectrometry by Combining Ion Enrichment, Discrimination Reduction, and Temporal Compression into a Single Gating Process, Analytical Chemistry, 2024, 96:10893-10900

[4]  Mei Li, Shuang Wang, Chuting Xu, Huiwen Ruan, Weiguo Wang*, Chuang Chen*, Haiyang Li*, Parallel Coupling of Ion Mobility Spectrometry and Ion Trap Mass Spectrometry for the Real-Time Alarm Triggering and Identification of Hazardous Chemical Leakages, Analytical Chemistry, 2021, 93: 11852

[5]  Mei Li, Wei Huang, Hong Chen, Dandan Jiang, Weiguo Wang, Yao Xiao, Chuang Chen*, Haiyang Li*, Dopant assisted photoionization ion mobility spectrometry for on-site specific and sensitive determination of atmospheric ammonia, Sensors and Actuators B: Chemical, 2021, 330: 129365

[6]  Chuang Chen, Mahmoud Tabrizchi*, Haiyang Li*, Ion gating in ion mobility spectrometry: Principles and advances, TrAC Trends in Analytical Chemistry, 2020, 133: 116100

[7]  Hong Chen, Chuang Chen*, Wei Huang, Mei Li, Yao Xiao, Dandan Jiang, Haiyang Li*, Miniaturized ion mobility spectrometry with a dual-compression tristate ion shutter for on-site rapid screening of fentanyl drug mixtures, Analytical Chemistry, 2019, 91: 9138-9146

[8]  Chuang Chen, Hong Chen, Dandan Jiang, Mei Li, Wei Huang, Haiyang Li*, Enhancing the sensitivity of ion mobility spectrometry using the ion enrichment effect of non-uniform electrostatic field, Sensors and Actuators B: Chemical, 2019, 295: 179-185

[9]  Chuang Chen#, Dandan Jiang#, Haiyang Li*, UV photoionization ion mobility spectrometry: Fundamentals and applications, Analytica Chimica Acta, 2019, 1077: 1-13

[10]  Hong Chen, Chuang Chen*, Mei Li, Weiguo Wang, Dandan Jiang, Haiyang Li*, Achieving high gating performance for ion mobility spectrometry by manipulating ion swarm spatiotemporal behaviors in the vicinity of ion shutter, Analytica Chimica Acta, 2019, 1052: 96-104

[11]  Chuang Chen, Hong Chen, Haiyang Li*, Pushing the resolving power of Tyndall-Powell gate ion mobility spectrometry over 100 with no sensitivity loss for multiple ion species, Analytical Chemistry, 2017, 89: 13398-13404

[12]  Chuang Chen, Mahmoud Tabrizchi*, Weiguo Wang, Haiyang Li*, Field switching combined with Bradbury-Nielsen gate for ion mobility spectrometry, Analytical Chemistry, 2015, 87: 7925-7930