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Capillary Electrophoresis Mass Spectrometry: A Highly Sensitive and Robust Analytical Platform

Posted: 2020-10-20

Time: 10:00 AM, Oct 20, 2020
Venue:No.4 Conference Room, Communication Center
Lecturer:Prof. David Da Yong Chen, Department of Chemistry, University of British Columbia

 

Abstract:

Different modes of capillary electrophoresis, such as free solution zone electrophoresis, high organic content CE, non-aqueous CE, and isoelectric focusing can all be easily coupled to mass spectrometry with a flow-through microvial all stainless steel interface. CEMS applications for metabolomics, proteomics, monoclonal antibody de novo sequencing, and monoclonal antibody charge state IEF analysis will be presented.

Introduction:

David Da Yong Chen received his Ph.D. in Chemistry in 1993 from University of Alberta, where he also received postdoctoral training in Chemistry and the Department of Medical Microbiology and Infectious Diseases. In July 1994, he joined the faculty of the Chemistry Department at the University of British Columbia, where he is currently a Full Professor in the Faculty of Science, as well as an Associate Member of the Department of Anesthesiology, Pharmacology & Therapeutics in the Faculty of Medicine. In December 2013, he was appointed Guest Professor at the School of Chemistry and Materials Science, Nanjing Normal University. Dr. Chen’s research interests include investigation of principles of fluid migration and chemical separation, development of novel instrumentation and analytical methods, and coupling micro separation systems to mass spectrometry. Dr. Chen was given the 2002 Royal Society of Chemistry (RSC) Award in Analytical Separation Methods, and the 2003 Charles McDowell Award for Excellence in Research, a gold medal given to the most outstanding young scientist at UBC. For his contribution in analytical chemistry, Dr. Chen received the W. A. E. McBryde Medal and the Maxxam Award from the Canadian Society for Chemistry in 2008 and 2015, respectively.

Contact: Prof. XU Guowang
Phone: 84379530