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Lecture: New Trends in the Preparation and Chromatographic Application of Porous Polymer Monoliths

Posted: 2015-09-30

Time: 11:00 September 30, 2015

Location: Conference Hall, Biotechnology Division

Reporter: Pro. Frantisek Svec, The Molecular Foundry, E.O. Lawrence Berkeley National Laboratory, Berkeley, USA

Biography:

Professor Frantisek Svec obtained his B.S. degree at Institute of Chemical Technology of Prague, and his Ph.D in polymer chemistry at Institute of Chemical Technology in Prague. He has been worked as Scientific Secretary and Technology Transfer Manager at Institute of Macromolecular Chemistry of Czech Academy of Sciences in Prague. From 1992 to 1996, he had been worked at Cornell University as a faculty. From 1996, he has been worked at University of California, Berkeley as a professor. Currently, he is a lead scientist and facility director at Molecular Foundry, E.O. Lawrence Berkeley National Laboratory. He is the President of California Separation Science Society, Editor-in-Chief of Journal of Separation Science, Memberships in Editorial Boards of Journal of Chromatography A and Electrophoresis. His main scientific interests include analytical and polymer chemistry, development of new separation media in various shapes and formats for different modes of separations, porous polymer monoliths, polymeric supports and catalysts, suspension, emulsion, and dispersion polymerization techniques, monodisperse beads, porous materials, chemical modification of polymers, microfluidic and capillary systems, and gas adsorption and storage. So far, he has published over 410 publications including 56 book chapters and review articles, 3 books, and 75 patents. His representative publications include those published on Science, Advanced Materials, Advanced Functional Materials, Chemistry of Materials, Analytical Chemistry, Macromolecules, Chemical Communications, Lab on a Chip, etc.

Abstract:

The modern monolithic columns emerged more than two decades ago. While the early polymer-based monoliths were used for the rapid separations of proteins, current literature describes a number of different applications in addition to typical liquid chromatography demonstrating versatility of the monoliths. For example, monolithic columns prepared using hypercrosslinking possess a large surface area in numerous mesopores and enable efficient rapid separation of small molecules. New chemistries are being developed to produce monolithic columns for the separation in various chromatographic modes. Modification of pore surface with nanostructures is another recent trend that extends applications of monoliths in the arena of highly selective fishing out systems. Large scale monolithic columns are now also available for industrial applications. Thin monolithic layers are gaining more attention since they enable efficient separations of proteins combined with mass spectrometry or SERS using very simple means. Monoliths also serve as supports for immobilization of enzymes to form very active enzymatic reactors.

Contact: Prof. Lihua Zhang (Group 1810, 84379720)