Time: 2015.9.16(Wed.)9:00 a.m.
Location: Meeting Room of The Laboratory of Biotechnology
Lecturer: Pro. Hong Li
Abstract:
The seminar will discuss what CRISPR-Cas pathway is and how it is being used in genome engineering. It also discusses biochemical and structural properties of the genome engineering enzymes and the pitfalls of the current technology based on the CRISPR-Cas machineries.
Introduction:
Professor Hong Li (Ph.D.) received B.S. in Physics from Sichuan University in 1983, M.S. in Physics from Ohio State University in 1989, and Ph.D. in Biophysics from University of Rochester in 1994 where she was a William F. Neuman fellow for academic excellence. Following postdoctoral training in the Department of Structural Biology at the Brookhaven National Laboratory and California Institute of Technology (with John N. Abelson), she became an Assistant Professor in 1999 and Full Professor in 2010 of Chemistry, Biochemistry, and Molecular Biophysics at Florida State University. She currently serves as the Director of the Molecular Biophysics Graduate Program at the Florida State University. She has contributed to understanding of gene expression and regulation by solving three-dimensional structures of many important protein and protein-nucleic acid complexes. Her research has appeared in high impact journals including Science, Nature, PNAS, Molecular Cell, and Nature Structure and Molecular Biology. She was the recipient of Young Investigator Award from the American Cancer Society, Scientist Development Award from the American Heart Association Florida/Ohio valley division, New Investigator Award from the Department of Florida Biochemical Research, Individual National Research Service Award from National Institutes of Health, and Developing Scholar Award from Florida State University. She is a permanent member of NIH MSFC study section and a recipient of multiple federal grants from NIH and NSF. Current research in Professor Li’s laboratory focuses on mechanisms and genome editing applications of the CRISPR-Cas pathway and ribosome production.
Contacts:Group1812 Song XUE (9069 )