Upcoming Events

Asymmetric Synthesis of Chiral Molecules Using Catalysts Based on Non-precious and Environmentally Friendly Metal--Discovery, Development and Creativity

Posted: 2014-03-27

Time March 28Friday10:00 am 

LocationEnergy Building 1#, 1st Floor Conference Room  

LecturerDr. Weiwei Zuo  

Department of Chemistry, University of Toronto, Canada 

Introduction 

Education: 

Ph.D. in Organometallics and Polymer Chemistry, Institute of Chemistry, CAS, China, Sept. 2005-Jun. 2008.  

Master of Polymer Physics, Donghua University, China, Sept.2002-Mar. 2005  

Bachelor of Science in Chemistry, Suzhou University, China, Sept. 1998-Jun. 2002  

Employment summary:  

Postdoctoral Associate in Organometallics and Catalysis, University of Toronto, Canada, Nov. 2011-present  

Postdoctoral Associate in Organometallics and Catalysis, University of Strasbourg, France, Jan. 2009-Jun. 2011.  

Areas of primary scientific interest: 

Green Chemistry, Asymmetric Catalysis, Iron based Organometallic Chemistry, Polymerization, Cross-Coupling Reactions Catalyzed by Iron based Catalysts.  

Abstract: 

Metal based homogeneous catalysts are used in the pharmaceutical, fragrance, flavoring, and fine chemicals industries for the synthesis of enantiomerically pure organic molecules such as alcohols, amines, and amino acids. Iron is an element essential to life and is abundant in mineral ores and thus its use is preferable for economic and health reasons. We validate a prior mechanistic hypothesis that partially saturated amine(imine)diphosphine ligands (P-NH-N-P) activate iron to catalyze the asymmetric reduction of the polar bonds of ketones and imines to valuable enantiopure alcohols, amines and amino acids, with isopropanol as the hydrogen donor, at turnover frequencies as high as 200 per second at 28°C. The author will share the expedience with the audience especially the students how to do research creatively, including where comes the initial idea, how the science was developed and what should we do in order to to a high-quality research.  

Contact:DNL1901 Xie Dong9583