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  English.dicp.cas.cn    Posted:2016-10-08
Proteomics as Diagnostic Tool for Platelet Function

Location: Conference Hall, Biotechnology Division, DICP

Time: 15:00, October 8, 2016

Speaker:Prof. Dr. Albert Sickmann

Bioanalytics, Leibniz-Institut für Analytische Wissenschaften -ISAS- e.V., Dortmund, Germany

Short Bio-sketch:

Education and career:

1999:                Diploma in Biochemistry

1999 - 2001:        PhD in Chemistry

2002 - 2003:        Junior Professor for protein function and Proteomics, Ruhr-University Bochum

2003 - 2008:        Groupleader for protein mass spectrometry at the Rudolf-Virchow Center, DFG Research Center for experimental Biomedicine, University of Würzburg

2007 - 2008:        Professor for protein mass spectrometry at the Rudolf-Virchow Center, DFG Research Center for experimental Biomedicine, University of Würzburg

Since 2008:        Professor for Bioanalytics at Leibniz-Institut für Analytische Wissenschaften -ISAS- e.V.

Since 2011:         President, Leibniz-Institut für Analytische Wissenschaften -ISAS- e.V.

Other Experience and Professional Memberships

Since 2010:        Member of the EuPA Executive Board

Since 2010:        Member of the Executive Board of the DGPF, Deutsche Gesellschaft für Proteomforschung e. V., President

Since 2010:        Member of the Scientific Advisory Board of the GBM, Gesellschaft für Biochemie und Molekularbiologie e.V.

Since 2015:         Associate Editor, Journal of Proteome Research

Research Interests:

OMICS technologies allow new insights in medical- and life science research. The key research interest is the analysis of complex biological systems in a precise way and technology development towards application, e.g. diagnostic tools for health research.


About 190 publication, around 7500 citations, h-Index: 51, author and editor of several books

5 selected publications (2006-2016)

(1)        Bj?rkqvist J, de Maat S, Lewandrowski U, Di Gennaro A, Oschatz C, Sch?nig K, N?then MM, Drouet C, Braley H, Nolte MW, Sickmann A, Panousis C, Maas C, Renné T.: Defective glycosylation of coagulation factor XII underlies hereditary angioedema type III. J Clin Invest. 125(8) (2015) 3132-46.

(2) Vaudel, M., Burkhart, J. M., Zahedi, R. P., Oveland, E., Berven, F. S., Sickmann, A., Martens, L., Barsnes, H.: PeptideShaker enables reanalysis of MS-derived proteomics data sets Nat.Biotech. 33 (1) (2015) 22-4

(3) Beck, F, Geiger, J., Gambaryan, S., Veit, J., Vaudel, M., Kohlbacher, O., Martens, L., Walter, U., Sickmann, A., Zahedi, R. P.: Time-resolved characterization of cAMP/PKA-dependent signaling reveals that platelet inhibition is a concerted process involving multiple signaling pathways Blood 2014 123 (5)

(4) Burkhart, J. M., Gambaryan, S., Watson, S. P., Jurk, K., Walter, U., Sickmann, A., Heemskerk, J. W. M., Zahedi, R. P.: What can Proteomics tell us about platelets? Circ. Res. 114 (2014) 1204-1219

(5) Schmidt, O.; A.B. Harbauer, A.B.; Rao, S.; Eyrich, B.; Zahedi, R. P.; Stojanovski, D.; Schonfisch, B.; Guiard, B.; Sickmann, A.; Pfanner, N.;Meisinger, C.:

Regulation of mitochondrial protein import by cytosolic kinases. Cell, 144(2) (2011) 227-39.

For further information, please contact Prof. Guowang Xu by 84379530.




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